Search Results - life+sciences

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Cervitude Imaging System (CIS) - A Method and Apparatus for Detecting Cervical Cancer
Background Cervical cancer is the fourth most frequent cancer in women worldwide representing 6.6% of all cancers affecting women. Most cervical cancer cases are caused by various strains of the human papillomavirus (HPV). According to the World Health Organization, mortality rates related to cervical cancer are higher in low- and middle-income countries...
Published: 7/27/2021   |   Inventor(s): Sesh Commuri, Garrett Winkelmaier
Keywords(s): Life Sciences
Category(s): Technology Classifications > Medical Devices
Development of Melioidosis Subunit Vaccines
Background: Burkholderia psuedomallei , the etiologic agent of melioidosis, causes severe disease in both humans and animals. Melioidosis is an emerging bacterial infectious disease that is being increasingly recognized in tropical regions around the world. Diagnosis and treatment of melioidosis can be challenging and no commercial vaccines currently...
Published: 6/24/2021   |   Inventor(s): Paul Brett, Mary Burtnick
Keywords(s): Life Sciences
Category(s): Technology Classifications > Life Sciences
Administration of Nootropic Agents for Enhancing Neuroprotective Signaling in Parkinson’s Disease
BackgroundParkinson’s Disease (PD) is a chronic, neurodegenerative disease, caused by the progressive loss of midbrain dopamine neurons in the substantia nigra, which sends axons to the striatum. Approximately 1% of Americans are afflicted with PD, which give rise to more than $14 billion in medical-related costs each year. Symptoms include irreversible...
Published: 6/24/2021   |   Inventor(s): Raul Dagda, Ruben Dagda
Keywords(s): Life Sciences
Category(s): Technology Classifications > Life Sciences
Compositions acting as (pro)renin receptor antagonists for the treatment of non-alcoholic fatty liver disease
BackgroundNon-alcoholic fatty liver disease (NAFLD) is an umbrella term for a range of liver conditions where excess fat is stored in the liver, and affects people with little to no alcohol use. Non-alcoholic steatohepatitis (NASH) is a potentially serious form of the disease that includes liver inflammation and potential scarring, cirrhosis, and liver...
Published: 6/24/2021   |   Inventor(s): Yumei Earley
Keywords(s): Life Sciences
Category(s): Technology Classifications > Life Sciences
Cyclic dominant negative competence stimulating peptide analogs to treat Streptococcus pneumoniae infections
Background Streptococcus pneumoniae (pneumococcus) is a bacterial pathogen responsible for many diseases in humans including pneumonia, meningitis, sepsis, and otitis media. It is a prevalent source of health and economic burden, with a death toll of >22,000 a year and >$3.5 billion in direct medical costs in the US alone. Concerns for current...
Published: 6/24/2021   |   Inventor(s): Yftah (Yiftah) Tal Gan, Gee Lau, Yifang Yang
Keywords(s): Life Sciences
Category(s): Technology Classifications > Life Sciences
Lateral Flow Immunoassay (LFI) for the Rapid Diagnosis of Plague
BackgroundIn the 14th century, plague was the cause of a pandemic wiping out 60% of Europe’s population. The bacterium responsible, Yersinia pestis, utilizes wild rodents as a natural reservoir and is primarily transmitted by fleas to other animal and human hosts. If administered early, antibiotics are effective at treating plague, but delayed...
Published: 6/24/2021   |   Inventor(s): David AuCoin, Marcellene Hollingsworth
Keywords(s): Life Sciences
Category(s): Technology Classifications > Life Sciences
Antigen Detection Assay for Early Point-of-Care Diagnosis of Zaire ebolavirus
Background The Ebola virus (EBOV) outbreak in West Africa from 2013 to 2016 and the multiple outbreaks in Democratic Republic of the Congo during 2018 have highlighted the need for a sensitive and rapid EBOV diagnostic test. Ideally, an EBOV Rapid test allows for point-of-care (POC) screening of patients and offers reliable sensitivity to support earlier...
Published: 6/24/2021   |   Inventor(s): David AuCoin, Marcellene Hollingsworth
Keywords(s): Life Sciences
Category(s): Technology Classifications > Life Sciences
Application to Control Shiga-toxin producing E. Coli O 157:H7, O26, O45, O103, O111, O121, and O145.
BackgroundBacterial resistance has developed towards antibiotics and chemical sanitizers due to their mass applications in food. Research is beginning to show that bacteria such as E. coli and Salmonella have both become resistant to lactic and peroxyacetic acid solutions, commonly used antimicrobial intervention in meat harvesting and processing plants....
Published: 3/19/2021   |   Inventor(s): Amilton de Mello, Erica Shebs
Keywords(s): Life Sciences
Category(s): Technology Classifications > Life Sciences
Engineered Tissue Succulence in Plants
Background: A novel technology to increase tissue succulence in plants using genetic engineering. Tissue succulence is an important plant trait that improves the drought attenuation of plants, improves salinity tolerance, and can optimize the performance of crassulacean acid metabolism. As climate change brings hotter and drier conditions to agricultural...
Published: 10/9/2020   |   Inventor(s): John Cushman, Sung Lim
Keywords(s): Life Sciences
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Agriculture
Use of in vivo Microbial Antigen Detection (InMAD) with human biological fluids for detection of circulating antigens
Background Diagnosis of an infection in a timely manner is essential for proper therapeutic administration and more effective treatments, especially for diseases with non-specific early symptoms. Acute infections are typically diagnosed by identifying microbial antigens directly from patient samples. However, microbes do not replicate to high levels...
Published: 5/12/2020   |   Inventor(s): David AuCoin, Thomas Kozel, Claire Smalley
Keywords(s): Life Sciences
Category(s): Technology Classifications > Life Sciences
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